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Cancer Vaccines

Celldex Therapeutics Regains Worldwide Rights to Rindopepimut CDX-110

Published in Vaccine Weekly, September 15th, 2010

Celldex Therapeutics, Inc. (NASDAQ:CLDX) announced it will regain full worldwide rights to develop and commercialize rindopepimut (CDX-110), effective November 1, 2010. Celldex and Pfizer Vaccines LLC entered into a global development and commercialization agreement in April 2008 for rindopepimut, an experimental therapeutic cancer vaccine that targets the tumor-specific molecule epidermal growth factor receptor variant III (EGFRvIII) in patients with Glioblastoma Multiforme (GBM). Pfizer has informed Celldex that the rindopepimut program is no longer a strategic priority of Pfizer and has terminated the agreement. As previously disclosed, across three clinical studies, rindopepimut has...

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