Investigators at Netherlands Vaccine Institute have published new data on whooping cough

Scientists discuss in 'Impaired long-term maintenance and function of Bordetella pertussis specific B cell memory' new findings in whooping cough. "Frequent occurrence of whooping cough in vaccinated populations suggests limited duration of vaccine-induced immunological memory. To investigate peculiarities in B cell memory specific for pertussis antigens P.69 pertactin (P.69 Prn), pertussis toxin (Ptx) and filamentous hemagglutinin (FHA), we monitored the induction and maintenance of specific serum IgG, long-lived bone marrow (BM)-derived plasma cell (PC) and splenic memory B cell (B(mem)) populations in a long-term preclinical vaccination model," investigators in Bilthoven, Netherlands...

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