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New findings reported from United States Army Medical Research Institute of Infectious Disease describe advances in vaccines

Published in Vaccine Weekly, October 6th, 2010

A report, 'Vector choice determines immunogenicity and potency of genetic vaccines against Angola Marburg virus in nonhuman primates,' is newly published data in The Journal of Virology. "The immunogenicity and durability of genetic vaccines are influenced by the composition of gene inserts and choice of delivery vector. DNA vectors are a promising vaccine approach showing efficacy when combined in prime-boost regimens with recombinant protein or viral vectors, but they have shown limited comparative efficacy as a stand-alone platform in primates, due possibly to suboptimal gene expression or cell targeting," scientists in the United States report.

"Here,...

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