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Immunoglobulins

Institute Pasteur describes research in immunoglobulins

Published in Vaccine Weekly, October 20th, 2010

New research, 'Characterization of botulinum neurotoxin type A neutralizing monoclonal antibodies and influence of their half-lives on therapeutic activity,' is the subject of a report. According to recent research from Paris, France, "Botulinum toxins, i.e. BoNT/A to/G, include the most toxic substances known."

"Since botulism is a potentially fatal neuroparalytic disease with possible use as a biowarfare weapon (Centers for Disease Control and Prevention category A bioterrorism agent), intensive efforts are being made to develop vaccines or neutralizing antibodies. The use of active fragments from non-human immunoglobulins (F(ab')(2), Fab', scFv), chemically modified...

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