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Gliomas

Findings from W. Maes and co-authors provide new insights into gliomas

Published in Vaccine Weekly, October 27th, 2010

New investigation results, 'DC vaccination with anti-CD25 treatment leads to long-term immunity against experimental glioma,' are detailed in a study published in Neuro-oncology. According to recent research published in the journal Neuro-oncology, "We studied the feasibility, efficacy, and mechanisms of dendritic cell (DC) immunotherapy against murine malignant glioma in the experimental GL261 intracranial (IC) tumor model. When administered prophylactically, mature DCs (DCm) ex vivo loaded with GL261 RNA (DCm-GL261-RNA) protected half of the vaccinated mice against IC glioma, whereas treatment with mock-loaded DCm or DCm loaded with irrelevant antigens did not result in...

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