Genetics and Cervical Cancer
Study confirms HPV genotypes responsible for majority of cervical cancers worldwide
Published in Vaccine Weekly, November 3rd, 2010
Eight human papillomavirus (HPV) types (16, 18, 45, 33, 31, 52, 58, and 35) are responsible for over 90% of all cervical cancer cases worldwide, and should be the target of the next generation vaccines, according to the largest study of HPV genotypes to date, published Online First in The Lancet Oncology. HPV 16, 18, and 45 are the most common types and occur at a much younger age than other high-risk HPV genotypes. As such, these three HPV types should be the focus of future type-specific HPV screening.
Cervical cancer is the second most common cancer among women worldwide, and is predicted to result in nearly 328 000 deaths in 2010. The disease is caused by high-risk...
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Source: Vaccine Weekly (2010-11-03)
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