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Genetics and Falciparum Malaria

New genetics and falciparum malaria study findings recently were reported by researchers at University of Oxford

Published in Vaccine Weekly, November 10th, 2010

New investigation results, 'New candidate vaccines against blood-stage Plasmodium falciparum malaria: prime-boost immunization regimens incorporating human and simian adenoviral vectors and poxviral vectors expressing an optimized antigen based on merozoite surface protein 1,' are detailed in a study published in Infection and Immunity. According to a study from Oxford, the United Kingdom, "Although merozoite surface protein 1 (MSP-1) is a leading candidate vaccine antigen for blood-stage malaria, its efficacy in clinical trials has been limited in part by antigenic polymorphism and potentially by the inability of protein-in-adjuvant vaccines to induce strong cellular immunity. Here...

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