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Immunization

Researchers' work from University of Wisconsin, Department of Oncology focuses on immunization

Published in Vaccine Weekly, November 10th, 2010

Fresh data on immunization are presented in the report 'Inhibition of gamma secretase blocks HPV infection.' According to a study from the United States, "Human papillomaviruses (HPV) are common sexually transmitted pathogens that predispose women to cervical and other anogenital cancers. HPV vaccines can prevent infection by some but not other sexually transmitted HPVs but are too costly for use in much of the world at greatest risk to HPV-associated cancers."

"Microbicides provide an inexpensive alternative to vaccines. In a high throughput screen, drugs that inhibit the cellular protein complex known as gamma secretase were identified as potential HPV microbicides....

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