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Herpes Zoster

Studies from University Medical Center provide new data on herpes zoster

Published in Vaccine Weekly, November 10th, 2010

A new study, 'Varicella-zoster virus neurotropism in SCID mouse-human dorsal root ganglia xenografts,' is now available. "Varicella-zoster virus (VZV) is a neurotropic human alphaherpesvirus and the causative agent of varicella and herpes zoster. VZV reactivation from latency in sensory nerve ganglia is a direct consequence of VZV neurotropism," scientists writing in the journal Current Topics In Microbiology and Immunology report.

"Investigation of VZV neuropathogenesis by infection of human dorsal root ganglion xenografts in immunocompromised (SCID) mice has provided a novel system in which to examine VZV neurotropism. Experimental infection with recombinant...

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