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Studies from N. Decarvalho and co-researchers yield new data on vaccines

Published in Vaccine Weekly, November 17th, 2010

"We report efficacy and immunogenicity of the HPV-16/18 ASO4-adjuvanted vaccine up to 7.3 years post-vaccination. The study was conducted in a population (N = 433) of women enrolled in Brazilian centres from an initial placebo-controlled study," researchers in Curitiba, Brazil report.

"Women were aged 15-25 years at first vaccination. During the most recent year of follow-up, approximately 7 years after initial vaccination, no cases of infection or cytohistological lesions associated with HPV-16/18 were observed in the vaccinees. Vaccine efficacy (95% confidence interval) up to 7.3 years was 94.5% (82.9, 98.9) for incident infection, 100% (55.7, 100) for 12-month...

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