Vaccines
New vaccines study findings have been reported from University of Illinois, Department of Biochemistry
Published in Vaccine Weekly, December 15th, 2010
2010 DEC 15 -- New investigation results, 'A single, engineered protein therapeutic agent neutralizes exotoxins from both Staphylococcus aureus and Streptococcus pyogenes,' are detailed in a study published in Clinical and Vaccine Immunology. "Staphylococcus aureus and Streptococcus pyogenes secrete exotoxins that act as superantigens, proteins that cause hyperimmune reactions by binding the variable domain of the T-cell receptor beta chain (Vß), leading to stimulation of a large fraction of the T-cell repertoire. To develop potential neutralizing agents, we engineered Vß mutants with high affinity for the superantigens staphylococcal enterotoxin...
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Source: Vaccine Weekly (2010-12-15)
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