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Cancer Vaccines

Research conducted by J. Tostain and co-researchers has updated our knowledge about cancer vaccines

Published in Vaccine Weekly, December 29th, 2010

2010 DEC 29 -- Current study results from the report, 'Carbonic anhydrase 9 in clear cell renal cell carcinoma: a marker for diagnosis, prognosis and treatment,' have been published. According to recent research from Saint Etienne, France, "Carbonic anhydrase 9 (CA9) is a transmembrane member of the carbonic anhydrase family. It catalyses the reversible hydration of carbon dioxide into bicarbonate and a proton, thus enabling tumor cells to maintain a neutral pH despite an acidic microenvironment."

"CA9 is not expressed in healthy renal tissue but is expressed in most clear cell renal cell carcinomas (CCRCC) through HIF-1a accumulation driven by hypoxia and...

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