Gene Therapy
Research from School of Medicine, Department of Pathology provide new insights into gene therapy
Published in Vaccine Weekly, January 5th, 2011
2011 JAN 5 -- Investigators publish new data in the report 'Efficient delivery of DNA vaccines using human papillomavirus pseudovirions.' According to a study from the United States, "We have examined non-replicative human papillomavirus (HPV) pseudovirions as an approach in the delivery of naked DNA vaccines without safety concerns associated with live viral vectors. In this study, we have generated HPV-16 pseudovirions encapsidating a DNA vaccine encoding the model antigen, ovalbumin (OVA) (HPV16-OVA pseudovirions)."
"Vaccination with HPV16-OVA pseudovirions subcutaneously elicited significantly stronger OVA-specific CD8+ T-cell immune responses compared...
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Source: Vaccine Weekly (2011-01-05)
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