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Viral Vaccines

Research from College of Medicine Provides New Data on Viral Vaccines

Published in Vaccine Weekly, January 26th, 2011

2011 JAN 26 -- Current study results from the report, 'Dendritic cell migration limits the duration of CD8+ T-cell priming to peripheral viral antigen,' have been published. "CD8(+) T cells (T(CD8(+))) play a crucial role in immunity to viruses. Antiviral T(CD8(+)) are initially activated by recognition of major histocompatibility complex (MHC) class I-peptide complexes on the surface of professional antigen-presenting cells (pAPC)," researchers in the United States report.

"Migration of pAPC from the site of infection to secondary lymphoid organs is likely required during a natural infection. Migrating pAPC can be directly infected with virus or may...

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