2011 JAN 26 -- Investigators publish new data in the report 'Vi-CRM 197 as a new conjugate vaccine against Salmonella Typhi.' "An efficacious, low cost vaccine against typhoid fever, especially for young children, would make a major impact on disease burden in developing countries. The virulence capsular polysaccharide of Salmonella typhi (Vi) coupled to recombinant mutant Pseudomonas aeruginosa exoprotein A (Vi-rEPA) has been shown to be highly efficacious," scientists in Siena, Italy report.
"We investigated the use of carrier proteins included in infant vaccines, standardized the conjugation process and developed key assays required for...
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