Vaccines

Kumamoto University Details Research in Vaccines

Published in Vaccine Weekly, February 9th, 2011

2011 FEB 9 -- According to a study from Honjo, Japan, "We examined the roles of a chemotherapeutic reagent in both inducing apoptosis and conferring acquired tumor immunity using mouse syngeneic tumor transplantation models. A chemotherapeutic reagent, cis-diamminedichloroplatinum (II), effectively induced apoptosis in Colon-26 cells originating from a BALB/c mouse."

"Three intradermal inoculations of cis-diamminedichloroplatinum (II)-treated Colon-26 cells conferred tumor immunity against viable Colon-26 cells in BALB/c mice but not in athymic BALB/c mice. The acquired immunity was Colon-26 cell specific and was adoptively transferable with splenic cells....

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Source: Vaccine Weekly (2011-02-09)

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