Lewis Lung Cancer
Reports Summarize Lewis Lung Cancer Study Results from Jiangsu University
Published in Vaccine Weekly, February 16th, 2011
2011 FEB 16 -- Research findings, 'Dendritic cells engineered to express GITRL enhance therapeutic immunity in murine Lewis lung carcinoma,' are discussed in a new report. "Glucocorticoid-induced tumor necrosis factor receptor and its ligand (GITRL) are critically involved in the regulation of immune response. In this study, we aimed to generate bone marrow-derived dendritic cells (BMDCs) transfected with recombinant adenovirus expressing GITRL (pAd-GITRL-BMDCs) and explore their therapeutic efficacy in murine Lewis lung carcinoma," scientists in Zhenjiang, People's Republic of China report.
"In vitro, pAd-GITRL-BMDCs greatly enhanced effector T cells...
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Source: Vaccine Weekly (2011-02-16)
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