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Research in the Area of Vaccines Reported from University of Groningen

Published in Vaccine Weekly, February 23rd, 2011

2011 FEB 23 -- "Gram-positive enhancer matrix (GEM) particles, produced from non-genetically modified Lactococcus lactis bacteria have an inherent immunostimulatory activity. It was investigated whether co-administration of GEM particles can reduce the amount of influenza subunit vaccine (HA) necessary to protect mice from viral infection," researchers in Netherlands report.

"Decreasing HA amounts of 5, 1, 0.2 and 0.04 mu g admixed with GEM particles were tested in intramuscular immunizations. Combinations of GEM and seasonal HA (A/Wisconsin/67/2005 [H3N2]) induced significantly higher systemic and better Th1/Th2-type balanced immune responses than HA...

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