Malaria Vaccines

Studies in the Area of Malaria Vaccines Reported from National Institute of Immunology

Published in Vaccine Weekly, March 9th, 2011

2011 MAR 9 -- Investigators publish new data in the report 'Serum and organ-associated anti-hemoglobin humoral autoreactivity: association with anti-Sm responses and inflammation.' "The release of hemoglobin (Hb) occurs in some infectious and autoimmune diseases characterized by inflammation. As levels of haptoglobin (Hp) fall, free Hb can cause pathology," investigators in New Delhi, India report.

"Humoral autoreactivity to human Hb was demonstrated in the sera of systemic lupus erythematosus (SLE), leishmania and malaria patients. Serum anti-murine Hb antibody levels in lupus-prone mice also exhibited an age-dependent increase, with progressive organ...

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Source: Vaccine Weekly (2011-03-09)

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