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Research on Vaccines Detailed by L.Y. Bai and Co-Authors

Published in Vaccine Weekly, March 16th, 2011

2011 MAR 16 -- According to recent research from Wuhan, People's Republic of China, "A novel somatostatin (SS) DNA vaccine (pGM-CSF/SS), delivered orally by attenuated Salmonella typhimurium (CSO22), was used to immunize female mice at 5, 7, and 11 wk of age; the objective was to investigate the humoral immune response and effects of this vaccine on growth, reproduction and lactation. The pGM-CSF/SS induced SS-specific antibodies, which peaked (3.69 +/- 0.89; mean +/- S.D) 4 wk after the first booster immunization."

"Compared with a saline-treated control group, body weight gain of a pGM-CSF/SS immunized group increased 30.3% (23.88 vs. 18.32 g, P< 0.05)...

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