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Tuberculosis

Scientists find candidate for new TB vaccine

Published in Vaccine Weekly, April 6th, 2011

2011 APR 6 -- Scientists have discovered a protein secreted by tuberculosis (TB) bacteria that could be a promising new vaccine candidate, they report in Proceedings of the National Academy of Sciences. The protein could also be used to improve diagnosis of TB.

TB is caused by the bacterium Mycobacterium tuberculosis (MTB), which infects the lungs and spreads through the air as a result of coughing. There are 9 million new cases of TB each year, killing 4,700 people a day worldwide.

BCG is the only available vaccine but it is of limited effectiveness in protecting against TB. BCG derives from the Mycobacterium bovis bacterium, which...

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