Vaccines

Researchers at McGill University Have Published New Data on Vaccines

Published in Vaccine Weekly, April 20th, 2011

2011 APR 20 -- "The ongoing evolution of BCG after its introduction in 1921 resulted in strains that differ genetically and phenotypically. Based on a genomic deletion (Region of Difference 2 or RD2) that occurred between 1927 and 1931, BCG strains can be sub-classified by the presence or absence of RD2," investigators in Montreal, Canada report.

"The existence of other mutations that distinguish BCG strains precludes simple comparison of RD2-positive and RD2-negative BCG strains to determine the importance, if any, of RD2 for vaccine protection. In this study, we have compared the RD2-containing BCG Russia, BCG Pasteur (which is a natural mutant for RD2),...

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Source: Vaccine Weekly (2011-04-20)

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