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Influenza Vaccines

New Findings from University of Wisconsin in the Area of Influenza Vaccines Described

Published in Vaccine Weekly, April 20th, 2011

2011 APR 20 -- Researchers detail in 'An M2 cytoplasmic tail mutant as a live attenuated influenza vaccine against pandemic (H1N1) 2009 influenza virus,' new data in Influenza Vaccines. "The 2009 influenza pandemic brought home the importance of vaccines in infection control. Previously, we demonstrated an M2 cytoplasmic tail mutant H5N1 influenza virus could serve as a live-attenuated vaccine," scientists in Madison, United States report.

"Here, we adapted that strategy, generating a mutant pandemic (H1N1) 2009 virus that grew well in cell culture, but replicated less well in mice than did wild-type virus. The mutant virus elicited sterile immunity in...

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