DNA Vaccines
Investigators at University Putra Malaysia Zero in on DNA Vaccines
Published in Vaccine Weekly, June 15th, 2011
2011 JUN 15 -- New investigation results, "DNA vaccine encoding avian influenza virus H5 and Esat-6 of Mycobacterium tuberculosis improved antibody responses against AIV in chickens," are detailed in a study published in Comparative Immunology, Microbiology and Infectious Diseases. "The H5 gene of avian influenza virus (AIV) strain A/chicken/Malaysia/5744/2004(H5N1) was cloned into pcDNA3.1 vector, and Esat-6 gene of Mycobacterium tuberculosis was fused into downstream of the H5 gene as a genetic adjuvant for DNA vaccine candidates. The antibody level against AIV was measured using enzyme-linked immunosorbent assay (ELISA) and haemagglutination inhibition (HI)...
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Source: Vaccine Weekly (2011-06-15)
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