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Study Results from Brigham and Women's Hospital Broaden Understanding of Vaccines

Published in Vaccine Weekly, June 22nd, 2011

2011 JUN 22 -- "Human immunodeficiency virus type 1 (HIV-1) vaccines directed to the cell-mediated immune system could have a role in lowering the plasma HIV-1 RNA set point, which may reduce infectivity and delay disease progression. Randomized, placebo-controlled trial involving HIV-1-infected participants who received a recombinant adenovirus serotype 5 (rAd5) HIV-1 gag vaccine or placebo," scientists writing in the Journal of Infectious Diseases report.

"Sequence-based HLA typing was performed for all 110 participants who initiated analytic treatment interruption (ATI) to assess the role of HLA types previously associated with HIV prognosis....

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