Cancer Vaccines
Studies from J.E. Boudreau et al Provide New Data on Cancer Vaccines
Published in Vaccine Weekly, June 29th, 2011
2011 JUN 29 -- According to recent research published in the journal Molecular Therapy, "Cancer immunotherapy aims to establish immune-mediated control of tumor growth by priming T-cell responses to target tumor-associated antigens. Three signals are required for T-cell activation: (i) presentation of cognate antigen in self MHC molecules; (ii) costimulation by membrane-bound receptor-ligand pairs; and (iii) soluble factors to direct polarization of the ensuing immune response."
"The ability of dendritic cells (DCs) to provide all three signals required for T-cell activation makes them an ideal cancer vaccine platform. Several strategies have been...
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Source: Vaccine Weekly (2011-06-29)
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