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New Vaccines Research from Mount Sinai School of Medicine Discussed

Published in Vaccine Weekly, July 6th, 2011

2011 JUL 6 -- Investigators publish new data in the report "Detection of prokaryotic mRNA signifies microbial viability and promotes immunity." According to the authors of recent research published in the journal Nature, "Live vaccines have long been known to trigger far more vigorous immune responses than their killed counterparts. This has been attributed to the ability of live microorganisms to replicate and express specialized virulence factors that facilitate invasion and infection of their hosts."

"However, protective immunization can often be achieved with a single injection of live, but not dead, attenuated microorganisms stripped of their...

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