Melanomas
Findings from L. Lattanzi and Co-Authors Provide New Insights into Melanomas
Published in Vaccine Weekly, July 20th, 2011
2011 JUL 20 -- According to the authors of recent research from Rome, Italy, "We have investigated the molecular mechanisms underlying the peculiar cross-presentation efficiency of human dendritic cells (DCs) differentiated from monocytes in the presence of Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) and Interferon (IFN)-alpha (IFN-DCs). To this end, we evaluated the capability of IFN-DCs to present and cross-present epitopes derived from Epstein-Barr Virus (EBV) or human melanoma-associated antigens after exposure to cell lysates or apoptotic cells."
"In an autologous setting, IFN-DCs loaded with Lymphoblastoid Cell Lines (LCL) lysates or...
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Source: Vaccine Weekly (2011-07-20)
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