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Reports on Vaccines Findings from University of Sheffield School of Medicine Provide New Insights

Published in Vaccine Weekly, August 10th, 2011

2011 AUG 10 -- Research findings, "Functional T-cell deficiency in adolescents who experience serogroup C meningococcal disease despite receiving the meningococcal serogroup C conjugate vaccine," are discussed in a new report. According to the authors of a study from Sheffield, United Kingdom, "Some individuals have experienced meningococcal disease despite receiving the meningococcal serogroup C conjugate (MCC) vaccine in adolescence. We sought to determine whether this is due to subclinical functional B-or T-cell immunodeficiency."

"Of 53 vaccine failures identified by enhanced surveillance of United Kingdom and Wales from 1999 to 2004, 15 received MCC...

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