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Hepatitis

New Hepatitis Data Have Been Reported by Researchers at University of Bristol

Published in Vaccine Weekly, August 31st, 2011

2011 AUG 31 -- Researchers detail in "A new cistron in the murine hepatitis virus replicase gene," new data in Hepatitis. According to the authors of recent research from Bristol, United Kingdom, "We report an RNA-negative, temperature-sensitive (ts) mutant of Murine hepatitis virus, Bristol ts31 (MHV-Brts31), that defines a new complementation group within the MHV replicase gene locus. MHV-Brts31 has near-normal levels of RNA synthesis at the permissive temperature of 33 degrees C but is unable to synthesize viral RNA when the infection is initiated and maintained at the nonpermissive temperature of 39.5 degrees C."

"Sequence analysis of MHV-Brts31 RNA...

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