Influenza
Researchers at University of Pennsylvania Have Published New Data on Influenza
Published in Vaccine Weekly, August 31st, 2011
2011 AUG 31 -- New research, "Prevalence of epistasis in the evolution of influenza A surface proteins," is the subject of a report. "The surface proteins of human influenza A viruses experience positive selection to escape both human immunity and, more recently, antiviral drug treatments. In bacteria and viruses, immune-escape and drug-resistant phenotypes often appear through a combination of several mutations that have epistatic effects on pathogen fitness," researchers in Philadelphia, Pennsylvania report.
"However, the extent and structure of epistasis in influenza viral proteins have not been systematically investigated. Here, we develop a novel...
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Source: Vaccine Weekly (2011-08-31)
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