Immunoglobulins
Recent Findings in Immunoglobulins Described by M. Schnaidt and Colleagues
Published in Vaccine Weekly, September 21st, 2011
2011 SEP 21 -- According to the authors of recent research published in the journal Transplantation, "Substantial progress in human leukocyte antigen antibody specification has been made by the introduction of Luminex single-antigen bead (SAB) assays. This progress was impaired when it turned out that this method is prone to a prozone effect leading to false-negative results in the case of high antibody titers."
"Testing serum and ethylenediaminetetraacetic acid (EDTA) plasma of one patient in parallel, we observed the prozone effect with the serum sample only. This led us to investigate complement component 1 (C1) as the cause of the prozone in SAB...
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Source: Vaccine Weekly (2011-09-21)
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