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Influenza Vaccines

Research from Scripps Research Institute Broadens Understanding of Influenza Vaccines

Published in Vaccine Weekly, September 28th, 2011

2011 SEP 28 -- Data detailed in "A highly conserved neutralizing epitope on group 2 influenza A viruses" have been presented. "Current flu vaccines provide only limited coverage against seasonal strains of influenza viruses. The identification of V(H)1-69 antibodies that broadly neutralize almost all influenza A group 1 viruses constituted a breakthrough in the influenza field," scientists in La Jolla, California report.

"Here, we report the isolation and characterization of a human monoclonal antibody CR8020 with broad neutralizing activity against most group 2 viruses, including H3N2 and H7N7, which cause severe human infection. The crystal structure of...

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