Researchers from Fred Hutchinson Cancer Research Center Report Details of New Studies and Findings in the Area of Vaccines

2011 SEP 28 -- Data detailed in "Mapping HIV-1 vaccine induced T-cell responses: bias towards less-conserved regions and potential impact on vaccine efficacy in the step study" have been presented. According to the authors of a study from Seattle, Washington, "T cell directed HIV vaccines are based upon the induction of CD8+ T cell memory responses that would be effective in inhibiting infection and subsequent replication of an infecting HIV-1 strain, a process that requires a match or near-match between the epitope induced by vaccination and the infecting viral strain. We compared the frequency and specificity of the CTL epitope responses elicited by the replication-defective...

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