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Francisella tularensis

Study Findings from University of Virginia Broaden Understanding of Francisella tularensis

Published in Vaccine Weekly, September 28th, 2011

2011 SEP 28 -- New research, "Impact of Francisella tularensis pilin homologs on pilus formation and virulence," is the subject of a report. "Francisella tularensis is a facultative intracellular bacterium and the causative agent of tularemia. Virulence factors for this bacterium, particularly those that facilitate host cell interaction, remain largely uncharacterized," scientists writing in the journal Microbial Pathogenesis report.

"However, genes homologous to those involved in type IV pilus structure and assembly, including six genes encoding putative major pilin subunit proteins, are present in the genome of the highly virulent Schu S4 strain....

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