2011 OCT 12 -- Research findings, "Virus-induced tumorinflammation facilitates effective DC cancerimmunotherapy in a Treg-dependent manner in mice," are discussed in a new report. According to the authors of recent research from Hannover, Germany, "Vaccination using DCs pulsed with tumor lysates or specific tumor-associated peptides has so far yielded limited clinical success for cancer treatment, due mainly to the low immunogenicity of tumor-associated antigens. In this study, we have identified intratumoral virus-induced inflammation as a precondition for effective antitumor DC vaccination in mice."
"Administration of a tumor-targeted DC vaccine during...
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