Pneumococcal Disease
Data on Pneumococcal Disease Described by Researchers at Children's Hospital
Published in Vaccine Weekly, October 19th, 2011
2011 OCT 19 -- Fresh data on Pneumococcal Disease are presented in the report "Expression of the type 1 pneumococcal pilus is bistable and negatively regulated by the structural component RrgA. 'The pneumococcal type 1 pilus, which is present in 25 to 30% of clinical isolates, has been associated with increased adherence and inflammatory responses and is being evaluated as a potential vaccine candidate. Here we show that expression of the pilus is bistable as a result of the molecular interaction between the transcription activator RrlA and a structural component of the pilus called RrgA," scientists in Boston, Massachusetts report.
"Sampling various...
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Source: Vaccine Weekly (2011-10-19)
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