2011 OCT 19 -- Current study results from the report, "Retinoic acid as a vaccine adjuvant enhances CD8+ T cell response and mucosal protection from viral challenge," have been published. According to the authors of recent research published in the Journal of Virology, "Vaccine-induced memory T cells localized at mucosal sites can provide rapid protection from viral infection. All-trans-retinoic acid (ATRA) has been shown to act physiologically to induce the expression of gut-homing receptors on lymphocytes."
"We tested whether the administration of exogenousATRA during a systemic vaccination of mice could enhance the generation of mucosal CD8(+) T...
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