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Molecular Imaging

Scientists at University of Western Ontario Publish New Data on Molecular Imaging

Published in Vaccine Weekly, November 2nd, 2011

2011 NOV 2 -- "An optimized non-invasive imaging modality capable of tracking and quantifying in vivo DC migration in patients would provide clinicians with valuable information regarding therapeutic DC-based vaccine outcomes. Superparamagnetic iron oxide (SPIO) nanoparticles were used to label bone marrow-derived DC," scientists writing in the journal Contrast Media & Molecular Imaging report.

"In vivo DC migration was tracked and quantified non-invasively using cellular magnetic resonance imaging (MRI) in a mouse model. Labelling DC with SPIO reflects the kinetics of DC migration in vivo but appears to reduce overall DC migration, in part due to...

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