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Cancer Vaccines

Studies from University of Pittsburgh School of Medicine Provide New Data on Cancer Vaccines

Published in Vaccine Weekly, November 2nd, 2011

2011 NOV 2 -- Researchers detail in "Poly-ICLC promotes the infiltration of effector T cells into intracranial gliomas via induction of CXCL10 in IFN-alpha and IFN-gamma dependent manners," new data in Cancer Vaccines. According to the authors of recent research published in the journal Cancer Immunology, Immunotherapy, "Stimulation of double-stranded (ds)RNA receptors can increase the effectiveness of cancer vaccines, but the underlying mechanisms are not completely elucidated. In this study, we sought to determine critical roles of host IFN-alpha and IFN-gamma pathways in the enhanced therapeutic efficacy mediated by peptide vaccines and polyinosinic-polycytidylic...

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