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Bacterial Vaccines

Research from Y. Fattahian and Co-Authors Reveals New Findings on Bacterial Vaccines

Published in Vaccine Weekly, November 30th, 2011

2011 NOV 30 -- According to the authors of a study from Tehran, Iran, "Acinetobacter baumannii, a major nosocomial pathogen, has remarkable capacity to acquire antimicrobial resistance attributable to its biofilm formation ability. Biofilm associated protein (Bap), a specific cell surface protein, is directly involved in biofilm formation by A. baumannii and plays a major role in bacterial infectious processes."

"In the present study we cloned, expressed and purified a 371 amino acid subunit of Bap. Mice were immunized using recombinant Bap subunit. They were then challenged with A. baumannii to evaluate the immunogenicity and protectivity of Bap subunit....

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