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Cytokines

Reports Outline Cytokines Research from Pennsylvania State University

Published in Vaccine Weekly, December 7th, 2011

2011 DEC 7 -- According to the authors of recent research from University Park, Pennsylvania, "Chemokine receptor CCR10 is expressed by all intestinal IgA-producing plasma cells and is suggested to play an important role in positioning these cells in the lamina propria for proper IgA production to maintain intestinal homeostasis and protect against infection. However, interfering with CCR10 or its ligand did not impair intestinal IgA production under homeostatic conditions or during infection, and the in vivo function of CCR10 in the intestinal IgA response remains unknown."

"We found that an enhanced generation of IgA(+) cells in isolated lymphoid...

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