Encephalitis
Study Data from University of Wyoming Provide New Insights into Encephalitis
Published in Vaccine Weekly, December 14th, 2011
2011 DEC 14 -- "In an effort to produce processed, soluble Western equine encephalitis virus (WEEV) glycoproteins for subunit therapeutic vaccine studies, we isolated twelve recombinant baculoviruses designed to express four different WEEV glycoprotein constructs under the transcriptional control of three temporally distinct baculovirus promoters. The WEEV glycoprotein constructs encoded full-length E1, the E1 ectodomain, an E26KE1 polyprotein precursor, and an artificial, secretable E2E1 chimera," investigators in Laramie, Wyoming report.
"The three different promoters induced gene expression during the immediate early (ie1), late (p6.9), and very late...
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Source: Vaccine Weekly (2011-12-14)
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