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Researchers at Tufts University Release New Data on Vaccines

Published in Vaccine Weekly, December 21st, 2011

2011 DEC 21 -- "Lyme disease is a major human health problem which continues to increase in incidence and geographic distribution. As a vector-borne zoonotic disease," researchers in North Grafton, Massachusetts report.

"Lyme disease may be amenable to reservoir targeted strategies for control. We have previously reported that a vaccinia virus (VV) based vaccine expressing outer surface protein A (OspA) of Borrelia burgdorferi, the causative agent of Lyme disease, protects inbred strains of laboratory mice against infection by feeding ticks and clears the ticks of infection when administered by gavage. Here we extend these studies to develop an effective...

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