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Salmonella

Research Data from Department Biochemistry Update Understanding of Salmonella

Published in Vaccine Weekly, January 4th, 2012

2012 JAN 4 -- According to the authors of recent research from Nanchang, People's Republic of China, "This study aimed to construct a live attenuated Salmonella typhimurium strain harbouring the Helicobacter pylori babA2 and ureI fusion gene, and to evaluate its immunogenicity. The babA2 and ureI fusion gene were cloned on an asd+ vector pYA3342 and expressed in attenuated S. typhimurium strain x8501 (Delta asd)."

"The level of babA2 and ureI fusion protein expression in S. typhimurium x8501 was examined by RT-PCR and Western blot tests. Stability of the recombinant x8501 (pYA3342/babA2/ureI) was determined after incubation for five days in vitro. The...

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