Published in Vaccine Weekly, January 11th, 2012
"However, despite extensive efforts, little progress has been made to improve efficacy since the first introduction of a live, attenuated vaccine in 1994 in the USA. Key limitations include: (a) uncertainty about the viral targets of protective immunity that prevents a research focus on individual viral structures and proteins, and frustrates efforts to design novel vaccines;...
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Source: Vaccine Weekly (2012-01-11)
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