Vaccines
Studies from North Carolina State University Provide New Data on Vaccines
Published in Vaccine Weekly, January 18th, 2012
2012 JAN 18 -- Research findings, "In vitro properties of a Listeria monocytogenes bacteriophage-resistant mutant predict its efficacy as a live oral vaccine strain," are discussed in a new report. "A Listeria monocytogenes glcV mutation precludes the binding of certain listerial phages and produces a profound attenuation characterized by the absence of detectable mutants in the livers and spleens of orally inoculated mice. In vitro, we found that the mutant formed plaques on mouse enterocyte monolayers as efficiently as the parent but the plaques formed were smaller," scientists in Raleigh, North Carolina report.
"Intracellular growth rate...
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Source: Vaccine Weekly (2012-01-18)
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