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Reports from Emory University Advance Knowledge in Vaccines

Published in Vaccine Weekly, January 25th, 2012

2012 JAN 25 -- Current study results from the report, "Vaccination alters the balance between protective immunity, exhaustion, escape, and death in chronic infections," have been published. "While T cell-based vaccines have the potential to provide protection against chronic virus infections, they also have the potential to generate immunopathology following subsequent virus infection. We develop a mathematical model to investigate the conditions under which T cells lead to protection versus adverse pathology," investigators in Atlanta, Georgia report.

"The model illustrates how the balance between virus clearance and immune exhaustion may be disrupted when...

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