Vaccines
Research from Institute of Health Biosciences Yields New Data on Vaccines
Published in Vaccine Weekly, February 8th, 2012
2012 FEB 8 -- Investigators discuss in "Mucosal immune features to phosphorylcholine by nasal Flt3 ligand cDNA-based vaccination" new findings in Vaccines. According to the authors of a study from Tokushima, Japan, "Phosphorylcholine (PC) is an immunodominant epitope in some pathogens including Streptococcus pneumoniae and it is well-known that PC-specific antibodies (Abs) play a key role in the induction of protective immunity against pneumococcal infection. In this study, we examined whether nasal administration of DNA plasmid encoding Flt3 ligand gene (pFL) as a mucosal adjuvant plus PC-conjugated keyhole limpet hemocyanin (PC-KLH), would elicit PC-specific immune...
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Source: Vaccine Weekly (2012-02-08)
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