Subunit Vaccines
Investigators at Institute for Molecular Biology Report Research in Subunit Vaccines
Published in Vaccine Weekly, February 22nd, 2012
2012 FEB 22 -- According to the authors of recent research from Aachen, Germany, "Several studies indicated that biopharmaceuticals based on the recombinant protein E7 of human papillomavirus (HPV) can serve as therapeutic vaccines preventing the development of cancer in women infected with high-risk types of HPV such as HPV16. Here, we report effective extraction and purification of a plant-produced E7GGG-lichenase fusion protein, an HPV16 subunit vaccine candidate, from Nicotiana benthamiana plants, to a high yield."
"The target contains the modified HPV16 E7 protein internally fused to the surface loop of a truncated, hexa-His- and KDEL-tagged variant of...
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Source: Vaccine Weekly (2012-02-22)
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